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Innovation with a Purpose
For more than two decades, Dr. Kenneth Binmoeller's clinical practice has driven innovations designed to make advanced endoscopic treatment more effective, less invasive, and more accessible.
The Physician as Inventor
Dr. Binmoeller identifies problems through everyday clinical practice and develops technologies and techniques to address them.
The clinical problem leads to an idea. The idea leads to engineering. Engineering leads to proof of concept. Proof of concept leads to patient impact.
Dr. Binmoeller has more than 50 patents for novel endoscopic technologies.
1
The Clinical Problem
2
The Idea
3
Engineering
4
Proof of Concept
5
Patient Impact
Mission Statements
Develop novel break-through techniques, procedures and devices that will prevent or treat digestive tract disease.
Conduct prospective outcomes studies to quantify the benefit of new techniques, procedures and devices on patient outcomes (including avoiding more invasive procedures and improved quality of life) and cost of health care.
Promote the integration of cutting-edge endoscopic care with the latest advances in nutritional and life-style strategies to defeat digestive tract disease
The Innovation Portfolio
A history of physician-driven innovation spanning devices, techniques, and technologies at various stages of development
Commercialized
AXIOS™ Lumen-Apposing Metal Stent
Dr. Binmoeller founded Xlumena around a portfolio of inventions for EUS-guided transluminal therapy. Xlumena was acquired by Boston Scientific in 2015, enabling global commercialization of the AXIOS™ lumen-apposing metal stent. This is one of the clearest examples of an Endovision-originated clinical idea becoming a widely commercialized medical technology.
Established
EUS-Guided Transluminal Therapy
Dr. Binmoeller's work in therapeutic EUS helped develop new approaches to accessing and treating structures through the gastrointestinal tract, including transluminal access, EUS-guided biliary drainage, EUS-guided cholecyst-enterostomy, and EUS-guided gastro-jejunostomy.
Established
EUS-Guided Coil & Glue Therapy
Dr. Binmoeller's innovations include EUS-guided coil and glue therapy, including treatment approaches for gastric varices. This work was specifically recognized in connection with his 2026 Rudolf Schindler Award.
Established
Underwater Endoscopy
Dr. Binmoeller developed and advanced water-aided / "underwater" endoscopic techniques, making difficult endoscopic procedures more effective and accessible. Endeau Inc. was created to develop devices and techniques for water-aided endoscopic procedures.
Established
Endoscopic Resection & Organ Preservation
Dr. Binmoeller has been a pioneer and educator in removing cancerous and precancerous growths endoscopically while preserving healthy anatomy. This includes EMR, ESD, resection of submucosal tumors, and treatment of dysplastic Barrett's esophagus — part of the larger evolution of advanced endoscopy.
Development
EndoSphere™ / SatiSphere™
EndoSphere was created around a group of patents designed to enable physiologic treatment of obesity and metabolic disease. The SatiSphere duodenal implant is identified by Endovision as having entered clinical trials.
Development
KBSolutions
KBSolutions was founded to develop a novel endoscopic tissue closure device — another example of Dr. Binmoeller's broader portfolio of device innovation.
Development
Endoscopic Access, Anchoring & Delivery
Dr. Binmoeller's patent portfolio includes concepts for tissue anchoring, luminal structure anchoring, stent deployment across adjacent tissue layers, transluminal access, needle-guided interventions, tissue sampling, and endoscopic device deployment.
The Philosophy Behind the Inventions
01
Novel
Meeting a need not adequately addressed by current technology.
02
Simple
Technically straightforward and intuitive.
03
Easy
Designed to be learnable and usable without unnecessary specialized complexity.
04
Cost Effective
Endoscopic therapy should offer advantages compared with more invasive treatment pathways where appropriate.
From AXIOS™ to What Comes Next
Past
AXIOS™
The original breakthrough that changed therapeutic endoscopy.
Present
Regenerative Endoscopy
Exploring biologic delivery for tissue repair.
Next
Next-Generation AXIOS™
A new development inspired by the original.
Future
New Physician-Driven Technologies
Continuing the model of clinical insight to patient impact.
Next-Generation AXIOS™ is a new development inspired by the experience of the original AXIOS™ — not the same device.
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